The Ballydoyle handler last year saddled six horses, including the winner, Wings Of Eagles, in the premier Classic.
And it could be similar scenario in the Derby on Saturday week, with O’Brien once again poised to be mob-handed.
Saxon Warrior will be O’Brien’s chief contender after he brilliantly won the 2000 Guineas at Newmarket.
O’Brien still has entered a clutch of other potential Derby runners, but plans at this stage remain fluid.
He said: “It depends upon what the lads (owners Coolmore) want to do, really, but obviously all those horses are born, bred and raised to be Derby horses.
“Obviously if they’re in good shape and they’re well, the lads like to give them their chance, like they did last year.
“I’m not sure what they’re really thinking at the moment
“The lads haven’t got together and spoke about what they want to do. I think that will happen towards the end of the week.”
Speaking at the Breakfast with the Stars event at Epsom on Tuesday morning, O’Brien issued a positive update on Saxon Warrior, who is odds-on favourite to provide his trainer with a seventh Derby success.
He said: “We are happy with Saxon Warrior and it’s so far, so good with all the possibles.
“We always thought he was a very high-quality colt and he’s done everything right so far.
“He’s a very strong blend of Danehill, Galileo and Deep Impact. We haven’t had anything like him before. He’s exciting. “